Cardiovascular disease is the leading cause of mortality in Ecuador. Beginning in 2019, PASB provided technical support for Ecuador’s adoption of the HEARTS initiative. By 2023, over 290,000 patients were participating, 75% of whom had achieved control of their hypertension. More than 48,000 health workers have been trained in HEARTS implementation through the PAHO Virtual Campus. Coordination, technical support, and evaluation of the national strategy was carried out by a management working group in partnership with the Ministry of Health, PAHO, and the University of Calgary. Training reached 478 health care facilities at the first level of care, with support from PAHO and Resolve to Save Lives.